Skip to main content
. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Hepatol. 2015 Mar 28;63(2):429–436. doi: 10.1016/j.jhep.2015.03.023

Fig. 1. Loss of FoxM1 expression in the HCC cells following MxCre induced deletion in transgenic mice expressing H-ras12V.

Fig. 1

Total RNA from (FoxM1+/+) normal liver, transgenic non-tumor and tumor tissues were assayed for expression of H-ras12V (A) and FoxM1 (B). FoxM1-mRNA (C) and H-ras12V-mRNA (D) levels without (FoxM1+/+) and with deletion of FoxM1 (FoxM1fl/fl) were compared. The RNAs were assayed by quantitative RT-PCR. (E) Tumor sections from FoxM1 undeleted (FoxM1+/+) and FoxM1 deleted (FoxM1fl/fl) samples were compared by immunohistochemcal staining for FoxM1. Arrows indicate fibroblast-like cells in tumor sections and arrowheads indicate the HCC cells.