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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2015 Apr 29;85:207–218. doi: 10.1016/j.freeradbiomed.2015.04.025

Figure 6. Effects of nitrite therapy on stored RBC mediated acute lung injury after trauma-hemorrhage.

Figure 6

Mice were exposed to trauma-hemorrhage and resuscitated with either saline or pRBC that were stored for either 0d or 5d and BAL levels of protein (Panel A) or inflammatory cell (Panel B), with differential analysis (Panel C–D) determined. Nitrite therapy was injected once immediately prior to transfusion at either 10µmol (□) or 100µmol (▪) injected amount per mouse. Note black bars are the same as data presented in Figure 5 and plotted here to improve ease of comparison of nitrite effects on pRBC-dependent acute lung injury test. #P<0.01 by 1-way ANOVA with Tukey post test. n= 3–12 per group.