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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2015 Apr 20;85:33–44. doi: 10.1016/j.freeradbiomed.2015.04.012

Figure 6. AUF-1 is involved in regulating SOD1 expression via the 3’UTR.

Figure 6

(A) Cells were transfected with the indicated siRNAs. 48 h after transfection, protein expression was detected by Western Blot in A2780 and PANC1 cells. (B) Relative SOD enzymatic activity after transfection of siRNA control or siRNA targeting AUF-1 in PANC1 and A2780 cells. (C) Luciferase reporters were co-transfected with scramble siRNA (control) or the siRNA targeting HuR or AUF-1 in A2780 cells. Luciferase activity was determined 48 h after transfection. Data represent mean ± SEM of three independent experiments, * P < 0.05, compared with scramble siRNA co-transfected cells.