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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Free Radic Biol Med. 2015 Apr 13;85:83–94. doi: 10.1016/j.freeradbiomed.2015.03.039

Figure 7. Trehalose mitigates decrease of cellular bioenergetics of Cl2 exposed H441 cells.

Figure 7

H441 cells were pre-treated with trehalose (Treh; 25 mM) or vehicle for 24 h and then exposed to either Cl2 (100 ppm, 15 min) or control (95%air/5% CO2). (A) Western blots at 1 h post Cl2. (B) Quantification of western blots shown in A. Values are means ± SEM; n=4. (C) Representative trace of OCR measurements of trehalose pre-treated cells 1 h post Cl2 exposure. All conditions are as described above. Values are means ± SEM; n=5–6 samples per group. (D) Bioenergetic profile from 3 independent experiments. Mean ± SEM; n=3 of oxygen consumption rates (expressed as % of basal). *p<0.05 compared to control, † p<0.05 compared to chlorine.