. 2015 Jul 20;53(8):2648–2658. doi: 10.1128/JCM.00591-15

TABLE 4.

Mutations in CAMP isolates^g

Mutation presence^a	Reference MRSA strain and position	Position^b	Change^c	Type	Proximal gene^d
Mutation presence^a	Reference MRSA strain and position	Position^b	Change^c	Type	Reference^e	N315^f	Name	Function
CAMP-18, not CAMP-19	FPR3757	357216	C→T	Intergenic	SAUSA300_0307	SA0295		Acid phosphatase?
		1181875	T→C	Synonymous	SAUSA300_1080	SA1029	ftsZ	Cell division
CAMP-19, not CAMP-18	FPR3757	1159271	C→T	Nonsynonymous	SAUSA300_1059	SA1009		Exotoxin?
		1777369	T→—	Frameshift	SAUSA300_1622	SA1499	tig	Molecular chaperone
		1858349	A→G	Synonymous	SAUSA300_1686	SA1561	murC	Cell wall synthesis
CAMP-28, not CAMP-29^h
CAMP-29, not CAMP-28	FPR3757	157471	C→A	Nonsynonymous	SAUSA300_0138	SA0131	deoD	Purine metabolism
		1043552	—→A	Intergenic	SAUSA300_0954	SA0904		Antibiotic resistance?
		1387815	G→A	Nonsynonymous	SAUSA300_1260	SA1197	tyrA	Shikimate pathway
		1768026	T→C	Synonymous	SAUSA300_1614	SA1491	hemL	Porphyrin biosynthesis
		2031280	T→A	Intergenic	SAUSA300_1871	SA1706
		2335992	G→A	Intergenic	SAUSA300_2158
		2348652	A→—	Intergenic	SAUSA300_2167
CAMP-36, not CAMP-37	252	142269	C→A	Intergenic	SAR0129	SA0122	butA	Acetoin formation
		1042026	T→—	Frameshift	SAR0994	SA0881
		2105113	C→T	Nonsynonymous	SAR2012	SA1735
CAMP-37, not CAMP-36	252	2707338	G→A	Nonsynonymous	SAR2622	SA2330		Transcriptional regulator?

CAMP-18, CAMP-28, and CAMP-36 are nares isolates. CAMP-19, CAMP-29, and CAMP-37 are wound isolates.

Nucleotide position on the chromosome of the reference strain. No mutations were observed on plasmids.

Nucleotide change on the Watson strand where sense (Watson or Crick) is defined by the reference. The convention used is [original]→[new], where “a to —” means there is a deletion and “— to a” means there is an insertion.

If mutation is in a gene, that gene; if mutation is in intergenic sequence between divergently or tandemly transcribed genes, the nearest downstream gene; and if mutation is in intergenic sequence between convergently transcribed genes, the nearest gene.

Name of gene in reference.

Name of orthologous gene in strain N315.

For more detailed descriptions, see Table S1 in the supplemental material.

No mutations were found in CAMP-28 that were not found in CAMP-29.