TABLE 4.
Sensitivity, specificity, and positive and negative predictive values
| Test | Sensitivity for CIN3+ (% [95% CI]) | Sensitivity for CIN2+ (% [95% CI]) | Specificity for <CIN2 (% [95% CI]) | PPV for CIN2+ (% [95% CI]) | NPV for <CIN2 (% [95% CI]) |
|---|---|---|---|---|---|
| LBC | 49.8 (34.7–64.9) | 39.5 (29.4–49.5) | 98.4 (98.1–98.7) | 22.7 (16.3–29.1) | 99.3 (99.1–99.5) |
| HR HC2 test | 100 (91.8–100) | 93.2 (87.1–99.2) | 94.9 (94.1–95.7) | 17.9 (14.5–21.4) | 99.9 (99.8–100) |
| AHPV test | 90.9 (81.1–100) | 87.8 (80.2–95.5) | 96.1 (95.5–96.7) | 21.1 (17.0–25.2) | 99.8 (99.7–100) |
| HPV 16 test | 59.0 (44.2–73.7) | 44.8 (34.5–55.1) | 99.2 (98.9–99.4) | 38.8 (29.4–48.1) | 99.3 (99.1–99.5) |
| HPV 16/18 test | 63.1 (48.6–77.6) | 49.7 (39.3–60.1) | 98.9 (98.6–99.2) | 35.2 (27.0–43.4) | 99.4 (99.2–99.6) |