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. 2015 Jul 20;53(8):2768–2772. doi: 10.1128/JCM.00647-15

TABLE 1.

Day of onset of symptoms and physical examination signs in eastern equine encephalitis

Symptom, observation, or outcome Hospital day of occurrence for patient:
1 2 3 4 5 6 7 8
Symptoms prior to hospitalizationa
    Fever or chills −1 −6 −1 −7 −1 −6 −1 −1
    Body ache None −6 −4 −7 None None −1 None
    Vomiting None −6 −3 −1 −4 −3 −1 None
    Diarrhea None None −1 None −4 None None −2
    Headache None −1 −1 −1 None −5 −1 −2
    Speech difficulty None None −1 −1 −1 None None −1
    Lassitude −1 −1 None −1 −1 −3 −7 None
    Seizure, localized or generalized −1 −2 None None −1 −4 None None
    Face weakness None None None None −1 None None None
    Arm weakness None None None −7 −1 None None None
    Leg weakness None None None −7 −1 None None None
Physical examination observations in hospitalb
    Ophthalmoplegia or paresis 2 2 1 1 1 1 1 3
    Meningismal signs None 1 1 1 None 1 1 2
    Focal or general motor seizure 1 1 5 None None 1 1 None
    Focal motor paresis or plegia 3 None 1 1 1 None 4 8
    Decorticate flexion signs 13 2 None None 2 1 None 3
    Decerebrate extension signs None 2 None None 2 1 None None
    Parkinsonian tremor 17 None None None None None None None
    Parkinsonian rigidity 9 None 1 None 4 1 None 6
    Stupor, arousable 1 1 1 1 1 1 None None
    Coma, unarousable 4 2 7 3 4 3 None None
    Edema, pitting 3 2 3 4 4 None None None
    Edema, nonpitting 4 None 3 6 4 3 None None
    Cyanosis 2 None None None None 6 None None
    Staccato hiccups None None 5 5 7 None None None
    Apneic episode 3 2 7 None 12 4 None None
Clinical outcomes
    Discharge from hospital 22 2 12 7 12 6 9 16
    Death 641c 2 12 7 12 6 No No
a

Each negative number designates the number of days prior to admission to the hospital that a symptom was first noted.

b

Each number designates the day in the hospital when a physical examination sign was first noted; the day of admission to the hospital was considered to be day 1 in the hospital.

c

Death occurred 641 days after admission to the hospital (619 days after discharge from the hospital) in a chronic nursing facility.