Table 1.
Baseline demographic characteristics of the ITT population
| Rivaroxaban (N = 124) | VKA (N = 124) | Total (N = 248) | P Value | |
|---|---|---|---|---|
| Mean age, years (SD) | 58.6 (9.9) | 60.5 (10.5) | 59.6 (10.2) | 0.211 |
| Age ≥75, n (%) | 5 (4.0) | 10 (8.1) | 15 (6.0) | 0.183 |
| Age 65–75 | 34 (27.4) | 41 (33.1) | 75 (30.2) | 0.183 |
| Male | 86 (69.4) | 90 (72.6) | 176 (71.0) | 0.576 |
| Caucasian | 112 (90.3) | 116 (93.5) | 228 (91.9) | 0.351 |
| Non-Hispanic/Latino | 90 (72.6) | 94 (75.8) | 184 (74.2) | 0.562 |
| Paroxysmal AF | 95 (76.6) | 87 (70.2) | 182 (73.4) | 0.250 |
| Prior cardioversion | 47 (37.9) | 54 (43.5) | 101 (40.7) | 0.366 |
| Prior catheter ablation | 11 (8.9) | 11 (8.9 | 22 (8.9) | 0.563 |
| Mean BMI, kg/m2 (SD) | 29.8 (5.7) | 28.9 (5.5) | 29.4 (5.6) | 0.231 |
| CHF | 12 (9.7) | 9 (7.3) | 21 (8.5) | 0.494 |
| Hypertension | 59 (47.6) | 57 (46.0) | 116 (46.8) | 0.799 |
| Mean systolic BP, mmHg (SD) | 133 (16) | 131 (18) | 132 (17) | 0.325 |
| Mean diastolic BP, mmHg (SD) | 81 (10) | 79 (11) | 80 (10) | 0.233 |
| Diabetes mellitus | 8 (6.5) | 14 (11.3) | 22 (8.9) | 0.180 |
| Prior Stroke/TIA/embolism | 0 | 3 (2.4) | 3 (1.2) | 0.081 |
| Vascular disease | 22 (17.7) | 25 (20.2) | 47 (19.0) | 0.627 |
| Mean CHADS2 Score (SD) | 0.7 (0.7) | 0.8 (0.9) | 0.7 (0.8) | 0.179 |
| Mean CHA2DS2-VASc Score (SD) | 1.5 (1.3) | 1.7 (1.4) | 1.6 (1.3) | 0.277 |
| Beta blocker, selective | 65 (52.4) | 61 (49.2) | 126 (50.8) | 0.611 |
| Antiarrhythmic, class IC | 51 (41.1) | 49 (39.5) | 100 (40.3) | 0.796 |
| Antiarrhythmic, class III | 30 (24.2) | 39 (31.5) | 69 (27.8) | 0.202 |
| Vitamin K antagonist | 36 (29.0) | 37 (29.8) | 73 (29.4) | 0.889 |
| Rivaroxaban | 23 (18.5) | 29 (23.4) | 52 (21.0) | 0.349 |
| Dabigatran | 12 (9.7) | 10 (8.1) | 22 (8.9) | 0.655 |
| Antiplatelet agent | 37 (29.8) | 29 (23.4) | 66 (26.6) | 0.250 |
| Proton pump inhibitor | 26 (21.0) | 18 (14.5) | 44 (17.7) | 0.184 |
Units are listed as n(%) unless otherwise indicated.
BMI, body mass index; BP, blood pressure; CHF, congestive heart failure; ITT, intention-to treat; SD, standard deviation.