Table 2.
Examples of miRNAs involved in CSC phenotype, and EMT process. This table focuses on few examples of miRNAs described in the text, with a particular attention on their function and the type of cancer where they have been found.
miRNA annotation | Function | Tumor | Ref. |
---|---|---|---|
let-7 | Regulator of self-renewal, cell proliferation and EMT | Lung, BC | 124 |
miR-34, miR-146a | Symmetric and asymmetric division of CSCs | colon | 132 |
miR-34, | Cell cycle control, invasion capacity and metastatic potential | BC | 133, 134 |
let-7, miR-10, miR-34, miR-200, miR-205; miR-30 | Stemness and EMT regulation | BC | 139, 141, 142 |
miR-155, miR-21 | EMT, cell migration and invasion control | BC | 133, 140 |