Table 1.
List of cases of acute demyelinating encephalomyelitis reported after recovery from malaria.
First author | Species | Age of patient | Time of neurological complication after recovery from malaria | MRI finding (T2-DWI) | Treatment | Outcome |
---|---|---|---|---|---|---|
Mohsen4 | P. falciparum | 30y | 8 weeks | Hyperintensities in subcortical white matter of right frontal and temporal lobes and left cerebellar hemisphere | No steroids | Complete neurological recovery |
Sharma9 | P. falciparum | 20y | 2 weeks | Hyperintensities of subcortical white matter, corpus callosum and midbrain | I/V methylprednisolone for 3 days | Complete neurological recovery |
Rachita10 | P. falciparum | 4y | 1 week | Hyperintensities in cerebral hemisphere, subcortical white matter and midbrain | I/V methylprednisolone for 3days, then oral steroids | Complete neurological recovery |
Agrawal11 | P. f alciparum | 12y | 16 days | Hyperintensities in perventricular white matter, centrum semiovale and genu of corpus callosum | I/V methylprednisolone for 5 days, then oral steroids | Complete neurological recovery |
Koibuchi12 | P. vivax | 24y | 2 weeks | Hyperintensities in left cerebral cortex and subcortex | Complete neurological recovery | |
Goyal6 | P. vivax | 18mo | 1 week | Diffuse white matter hyperintensities fof subcortical deep and periventricular white matter and both external capsules | I/V methylprednisolone for 3 days, then oral steroids for 2 weeks | Complete neurological recovery |
y, years; mo, months; MRI, magnetic resonance imaging.