Table 4.
Hematologic toxicities after chemotherapy
| MPV3 (n = 23) | MTX5 (n = 15) | Fisher’s test results | |
|---|---|---|---|
| After MPV / MTX | |||
| Neutropenia G3 | 3 (13%) | 3 (20%) | n.s. |
| G4 | 1 (4%) | 0 (0%) | n.s. |
| Thrombocytopenia G3 | 1 (4%) | 0 (0%) | n.s. |
| G4 | 0 (0%) | 0 (0%) | n.s. |
| Anemia G3 | 1 (4%) | 0 (0%) | n.s. |
| G4 | 0 (0%) | 0 (0%) | n.s. |
| After Ara-C | |||
| Neutropenia G4 | 16/18 (89%) | 12/13 (92%) | n.s. |
| Thrombocytopenia G4 | 5 /18 (28%) | 2/13 (15%) | n.s. |
| Anemia G4 | 0/18 (0%) | 0/13 (0%) | n.s. |
| Non-hematologic toxicity | |||
| Nausea G3 | 4 (17%) | 2 (15%) | n.s. |
| Liver dysfunction G3 | 3 (13%) | 0 (0%) | n.s. |
| DVT G2 | 1 (4%) | 0 (0%) | n.s. |
| Numbness G3 | 0 (0%) | 1 (7%) | n.s. |
| Drug eruption G2 | 0 (0%) | 2 (13%) | n.s. |
| Photodermatosis G2 | 0 (0%) | 1 (7%) | n.s. |
| Fever | 0 (0%) | 0 (0%) | n.s. |
DVT: deep venous thrombosis, G2: grade 2, G3: grade 3, G4: grade 4, MPV: methotrexate + procarbazine + vincristine, MTX: methotrexate, n.s.: not significant.