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. Author manuscript; available in PMC: 2016 Jul 2.
Published in final edited form as: Cell. 2015 Jun 18;162(1):184–197. doi: 10.1016/j.cell.2015.05.047

Fig. 7. Frequency of IFPCs identifies a gene expression signature that predicts clinical outcome.

Fig. 7

(A) IFPC gene signature identified by deconvolution of bulk expression data using IFPC frequency. The heat map displays expression of each gene in the bulk measurements. Rows are alphabetically ordered; columns are ordered by the mean expression of the genes in the signature. (B) The mean of the IFPC signature forms a clinically significant prognostic indicator of overall survival in 2 independent cohorts of adult AML (Metzeler et al., 2008). Patients were assigned to groups for Kaplan-Meier analysis based on whether their IFPC expression score was below or above the cohort median. P values obtained from log-rank test.