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. 2015 Jul 20;210(2):303–318. doi: 10.1083/jcb.201411001

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© 2015 Gomez-Lamarca et al.

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Figure 6. — Combined depletion of Rme-8 with ESCRT-0 results in ectopic Notch activation and tissue overgrowth. (A–F′) NRE-GFP (A–C) and Wg (D–F) expression are strongly up-regulated in Hrs+Rme-8 double knockdown (B and E) and Stam+Rme8 double knockdown (C and F), in contrast to the Hrs single knockdown where expression is unaffected (A and D, Hrs-Ri;w-Ri).