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. 2015 Jul 20;210(2):303–318. doi: 10.1083/jcb.201411001

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© 2015 Gomez-Lamarca et al.

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Figure 8. — Ectopic Notch activation observed in combined depletions is not prevented by Kuz^DN. (A–D′) NRE-GFP expression shows that ectopic Notch activation in StamRi+Rme-8-Ri (A) or Vps26-Ri+Rme-8-Ri (C) is not rescued by kuz^DN coexpression (B and D). (E) Wg D/V expression is lost in discs expressing kuz^DN alone. (F and G) kuz^DN coexpression rescues overgrowth caused by Hrs-Ri+Rme-8-Ri. (H) Quantification of wing disc size for genotypes shown in F and G. Boxes indicate 25th to 75th percentiles, whiskers represent maximum and minimum values in the dataset, and lines show the median values. Asterisks indicate significance according to t test; ****, P < 0.0001.