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. 2015 Jul 21;5:12376. doi: 10.1038/srep12376

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(A) Schematic of the ancestry enrichment technique. Ancestry-enriched regions are identified as genomic loci with anomalously high ancestry contributions, for the entire population, from one of the three continental components. (B) Heatmap showing the population frequencies of three-way ancestry proportion combinations for Colombian genomes. Each block corresponds to a specific three-way ancestry proportion combination, and the frequency of that combination in the population is color-coded as shown in the scale adjacent to the heatmap. Note that since there are three continental ancestry components, the value of the third ancestry component (European) is dependent on the first two and thus not shown. (C) Manhattan plot showing the genomic regions identified as ancestry-enriched via the trinomial probability (y-axis) of observing a particular three-way ancestry combination in the population (see Materials and Methods).