Table II.
Differentially expressed genes that overlap between the main pathway (Pathways in cancer) and 9 other pathways.
| KEGG ID | Term | Overlap DEGs | Count |
|---|---|---|---|
| 04510 | Focal adhesion | IGF1, EGFR, LAMA2, PTEN, MAPK10, LAMA4, LAMC1, MET, LAMA3, LAMB2, BCL2, PDGFA, COL4A6, FN1, PIK3R1, PDGFRA, JUN, COL4A2, LAMB3, VEGFC, ITGA6 | 21 |
| 05222 | Small cell lung cancer | LAMA2, LAMA4, LAMC1, PTGS2, LAMB3, LAMA3, LAMB2, BCL2, ITGA6, COL4A6, CCNE2, FN1, E2F3, PTEN, COL4A2, PIK3R1 | 16 |
| 05215 | Prostate cancer | IGF1, FOXO1, TCF7L2, BCL2, FGFR1, EGFR, PDGFRA, PDGFA, PTEN, TCF7L1, CCNE2, LEF1, E2F3, PIK3R1 | 14 |
| 05218 | Melanoma | IGF1, EGFR, FGF2, PTEN, FGF1, MET, PDGFRA, FGFR1, PIK3R1, MITF, PDGFA, E2F3, CDKN2A | 13 |
| 04512 | ECM-receptor interaction | LAMA2, COL4A2, LAMA4, LAMC1, LAMB3, LAMA3, LAMB2, ITGA6, COL4A6, FN1 | 10 |
| 05221 | Acute myeloid leukemia | ZBTB16, CEBPA, RUNX1T1, TCF7L2, STAT5A, STAT5B, TCF7L1, KIT, PIK3R1, LEF1 | 10 |
| 04916 | Melanogenesis | FZD4, TCF7L2, FZD5, TCF7L1, KIT, MITF, FZD7, LEF1 | 8 |
| 04520 | Adherens junction | EGFR, TCF7L2, TGFBR, MET, TCF7L1, FGFR1, LEF1 | 7 |
| 05219 | Bladder cancer | EGFR, VEGFC, MMP1, MMP9, FGFR3, E2F3, CDKN2A | 7 |
KEGG, Kyoto Encyclopedia of Genes and Genomes; ECM, extracellular matrix.