Table II.
Comparison of MVD, EA and Ki-67-positive cells in PDAC tissue and ANT.
Tissue type | MVD (no. of microvessels) | EA (µ2) | Ki-67 positive fraction (no. of MIB-1-positive nuclei) |
---|---|---|---|
ANT | 8±4 | 73.12±27.88 | 15±6 |
PDAC | 27±8 | 186.06±65.89 | 66±25 |
P-value | 0.001 | 0.003 | 0.001 |
Values are presented as the mean ± standard deviation and statistical comparisons were performed using the Student's t-test. Results were counted in highly vascularised ‘hot spots’ at x400 magnification (0.19 mm2 area; n=5). MVD, microvascular density; EA, endothelial area; ANT, adjacent normal tissue; PDAC, pancreatic ductal adenocarcinoma.