Table 1.
Group※ | C0 | C1 | ∆C | ∆C% | P value |
---|---|---|---|---|---|
| |||||
(C1-C0) | ∆C/C0×100% | ||||
GPBS | 0.25±0.01 | 0.24±0.03 | -0.01±0.02 | -5.22±6.75 | 0.600 |
Brimonidine | 0.25±0.02 | 0.33±0.04 | 0.07±0.02 | 26.65±6.32 | 0.010* |
Latanoprost | 0.24±0.03 | 0.37±0.04 | 0.12±0.02 | 54.2±11.5 | 0.001* |
Levobunolol | 0.24±0.02 | 0.25±0.02 | 0.01±0.01 | 4.07±4.45 | 0.390 |
Brinzolamide | 0.22±0.01 | 0.23±0.02 | 0.01±0.02 | 1.23±6.79 | 0.770 |
Pilocarpine | 0.24±0.02 | 0.25±0.01 | 0.01±0.01 | 2.32±6.06 | 0.380 |
5.5 mM GPBS and GPBS with corresponding concentration eye drops (4.9×103 nM Brimonidine, 41.1 nM Latanoprost, 3.4×103 nM Levobunolol, 3.0×103 nM Brinzolamide and 8.3×103 nM Pilocarpine1).
For 4.9×103 nM Brimonidine and 41.1 nM Latanoprost showed statistical differences between C0 and C1, their concentration was reduced 3 times, while other drugs concentration was improved 10 times to confirm its effectiveness further. Pre-operation (C0), Post-operation (C1); P < 0.05.