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. 2015 May 15;8(5):7184–7191.

Table 1.

Summary of facility neasurements, before and after drug treatments (mean ± SEM, μl·min-1·mmHg-1, n = 6)

Group C0 C1 ∆C ∆C% P value

(C1-C0) ∆C/C0×100%
GPBS 0.25±0.01 0.24±0.03 -0.01±0.02 -5.22±6.75 0.600
Brimonidine 0.25±0.02 0.33±0.04 0.07±0.02 26.65±6.32 0.010*
Latanoprost 0.24±0.03 0.37±0.04 0.12±0.02 54.2±11.5 0.001*
Levobunolol 0.24±0.02 0.25±0.02 0.01±0.01 4.07±4.45 0.390
Brinzolamide 0.22±0.01 0.23±0.02 0.01±0.02 1.23±6.79 0.770
Pilocarpine 0.24±0.02 0.25±0.01 0.01±0.01 2.32±6.06 0.380

5.5 mM GPBS and GPBS with corresponding concentration eye drops (4.9×103 nM Brimonidine, 41.1 nM Latanoprost, 3.4×103 nM Levobunolol, 3.0×103 nM Brinzolamide and 8.3×103 nM Pilocarpine1).

For 4.9×103 nM Brimonidine and 41.1 nM Latanoprost showed statistical differences between C0 and C1, their concentration was reduced 3 times, while other drugs concentration was improved 10 times to confirm its effectiveness further. Pre-operation (C0), Post-operation (C1); P < 0.05.