Table 5.
Relationship between APOBEC3 and HCC clinico-pathological characteristics by logistic regression analysis
| APOBEC3 | Vascular invasion | |||
|
| ||||
| Univariate analysis, OR (95% CI) | P value | Multivariate Analysis, OR (95% CI) | P value | |
|
| ||||
| A3F, per increase of 1 unit | 3.776 (0.818-17.435) | 0.089 | 5.379 (1.111-26.039) | 0.037 |
| A3H, per increase of 1 unit | 0.263 (0.069-1.009) | 0.051 | 0.197 (0.049-0.798) | 0.023 |
|
| ||||
| APOBEC3 | Intrahepatic metastasis | |||
|
| ||||
| Univariate analysis, OR (95% CI) | P value | Multivariate Analysis, OR (95% CI) | P value | |
|
| ||||
| A3F, per increase of 1 unit | 4.263 (0.758-23.989) | 0.1 | 6.741 (1.111-40.885) | 0.038 |
| A3H, per increase of 1 unit | 0.14 (0.022-0.885) | 0.037 | 0.101 (0.015-0.66) | 0.017 |
|
| ||||
| APOBEC3 | AFP over 200 ng/ml | |||
|
| ||||
| Univariate analysis, OR (95% CI) | P value | Multivariate Analysis, OR (95% CI) | P value | |
|
| ||||
| A3B, per increase of 1 unit | 0.473 (0.246-0.911) | 0.025 | 0.53 (0.277-1.014) | 0.055 |
| A3F, per increase of 1 unit | 5.897 (1.233-28.191) | 0.026 | 7.685 (1.483-39.823) | 0.015 |
| A3H, per increase of 1 unit | 0.226 (0.05-1.015) | 0.052 | 0.166 (0.034-0.81) | 0.026 |