Table III.

Pooled OR data obtained in the current meta-analysis.

Contrast model	Studies, n	OR (95% CI)	P-value	Model	I2, %	P-value
Total studies
Homozygous	27	1.39 (1.20–1.62)	<0.001	Random	41.5	0.011
Heterozygous	27	1.18 (1.05–1.32)	0.006	Random	47.3	0.003
Recessive	27	1.26 (1.12–1.42)	<0.001	Random	34.1	0.039
Dominant	27	1.23 (1.10–1.38)	<0.001	Random	52.8	0.016
Caucasian
Homozygous	12	1.15 (0.89–1.48)	0.791	Random	58.2	0.006
Homozygous (adjusted for heterogeneity)	10	1.13 (0.93–1.36)	0.215	Fixed	10.6	0.345
Heterozygous	12	1.03 (0.84–1.25)	<0.001	Fixed	0.0	0.674
Recessive	12	1.09 (0.91–1.31)	0.367	Fixed	32.1	0.134
Dominant	12	1.05 (0.86–1.28)	0.609	Random	63.3	0.002
Dominant (adjusted for heterogeneity)	10	1.00 (0.88–1.14)	0.968	Fixed	27.6	0.19
Asian
Homozygous	17	1.64 (1.43–1.90)	<0.001	Fixed	0.0	0.674
Heterozygous	17	1.30 (1.16–1.45)	<0.001	Fixed	2.6	0.423
Recessive	17	1.41 (1.25–1.61)	<0.001	Fixed	8.1	0.361
Dominant	17	1.39 (1.25–1.54)	<0.001	Fixed	0.0	0.729

OR, odds ratio; CI, confidence interval; I², index of heterogeneity.