Table I.
Clinicopathological factors associated with B7-H3 and TLT-2 protein expression levels.
| B7-H3 | TLT-2 | |||||
|---|---|---|---|---|---|---|
| Factor | Normal | Increased | P-value | Normal | Increased | P-value |
| Tumor location | 0.499a | 0.371a | ||||
| Tongue | 14 | 24 | 16 | 22 | ||
| Gingiva | 2 | 6 | 4 | 4 | ||
| Buccal mucosa | 3 | 14 | 5 | 12 | ||
| Palate | 2 | 2 | 1 | 3 | ||
| Floor of the mouth | 4 | 5 | 1 | 8 | ||
| Tumor size | 0.135b | 0.212b | ||||
| T1 | 10 | 9 | 9 | 10 | ||
| T2 | 10 | 21 | 12 | 19 | ||
| T3 | 4 | 17 | 6 | 15 | ||
| T4 | 1 | 4 | 0 | 5 | ||
| Nodal status | 0.026c | 0.021c | ||||
| N0 | 17 | 18 | 18 | 17 | ||
| N1 | 6 | 26 | 8 | 24 | ||
| N2 | 2 | 7 | 1 | 8 | ||
| Metastatic status | 0.073d | 0.057d | ||||
| M0 | 25 | 45 | 27 | 43 | ||
| M1 | 0 | 6 | 0 | 6 | ||
| Histological differentiation | 0.011e | 0.016e | ||||
| High | 21 | 25 | 22 | 24 | ||
| Moderate | 4 | 22 | 5 | 21 | ||
| Low | 0 | 4 | 0 | 4 | ||
a
P>0.05 vs. tongue.
b
P>0.05 vs. T1.
c
P<0.05 vs. N0.
d
P>0.05 vs. M0.
e
P<0.05 vs. high. Tumor Node Metastasis classification of malignant tumors was used to classify the tumor size, nodal status and metastasis status. TLT-2, triggering receptor expressed on myeloid cell-like transcript-2.