Table 4.
No. of Neurons |
|||||
---|---|---|---|---|---|
Drug | Type of Response | pSPN | pFSI | pChAT | Unidentified |
DEP20 | Days 1–14 | ||||
Activated (14/154, 9%) | 10/47 (21%)# | 1/37 (3%) | 1/36 (3%) | 2/34 (6%) | |
Inhibited (104/154, 68%)* | 24/47 (51%) | 24/37 (65%) | 28/36 (78%) | 28/34 (82%) | |
Days 1–7 | |||||
Activated (14/131, 11%) | 10/41 (24%)# | 1/34 (3%) | 1/27 (4%) | 2/29 (7%) | |
Inhibited (82/131, 63%)* | 18/41 (44%) | 21/34 (62%) | 20/27 (74%) | 23/29 (79%) | |
PHEN20 | Days 1–7 | ||||
Activated (3/59, 5%) | 1/16 (6%) | 0/9 (0%) | 0/19 (0%) | 2/15 (13%) | |
Inhibited 38 (38/59, 64%)* | 11/16 (69%) | 5/9 (55%) | 16/19 (84%) | 6/15 (40%) | |
BUP30 | Days 1–7 | ||||
Activated (16/110, 15%) | 8/42 (19%) | 4/20 (20%) | 0/19 (0%) | 4/29 (14%) | |
Inhibited (48/110, 44%)* | 13/42 (31%) | 6/20 (30%) | 14/19 (74%) | 15/29 (52%) |
Values are no. of neurons per indicated population within each cell type, with percentages given in parentheses.
P < 0.05, comparison between activated vs. inhibited neurons.
P < 0.05, comparison across all 4 putative cell types.