Figure 3.

Repression of colon tumor growth by Salmonella strains in mice with a small tumor. CT26 colon tumor initial size ~100 mm³ in (A) nude mice or (B) BALB/c mice. Nude mice were treated with single-shot YB1 (n=5, mean ± standard deviation). BALB/c mice were injected with PBS, YB1, VNP20009 or SL7207 (n=5 each; mean ± standard deviation). (C) On day 12 after treatment, the mice of each group were euthanized and the bacteria in the organs were counted. **P<0.01 and ***P<0.001, PBS vs. YB1, VNP20009 or SL7207 group; ^###P<0.001, YB1 vs. VNP20009 group. PBS, phosphate-buffered saline.