Table I.
Comparison of clinical characteristics between the two groups.
| Clinical parameter | PCI group, n=66 | Control group, n=17 | P-value |
|---|---|---|---|
| Basic clinical characteristics | |||
| Age, years | 59.54±9.06 | 57.32±6.30 | NS |
| Male (%) | 49 (74.2) | 11 (68.7) | NS |
| BMI, kg/m2 | 24.6±3.4 | 23.9±2.8 | NS |
| Hypertension (%) | 35 (53) | 7 (43.8) | NS |
| ACEI or ARB treatment (%) | 29 (43.9) | 7 (43.8) | NS |
| Diabetes (%) | 24 (36.4) | 2 (11.8) | <0.05 |
| Current smoker (%) | 20 (30.3) | 4 (23.5) | NS |
| Family history of coronary disease (%) | 5 (31.3) | 2 (5.9) | <0.05 |
| Single-vessel disease (%) | 36 (54.5) | 5 (31.2) | <0.05 |
| Two-vessel disease (%) | 16 (24.2) | 2 (12.5) | <0.05 |
| Three-vessel disease (%) | 14 (18.75) | 1 (6.25) | <0.05 |
| Statin therapy prior to PCI (%) | 66 (100) | 17 (100) | NS |
| Laboratory characteristics | |||
| Plasma low density cholesterol, mmol/l | 2.54±0.81 | 2.21±0.32 | NS |
| Hs-CRP, mg/l | 1.55±2.83 | 0.62±0.78 | NS |
| White cell count (x109/l) | 6.63±1.35 | 6.39±1.23 | NS |
| Lymphocyte count (x109/l) | 1.62±0.44 | 1.64±0.31 | NS |
| Monocyte count (x109/l) | 0.50±0.4 | 0.51±0.32 | – |
| Maximum value of CKMB pre-PCI, U/l | 22 | 19 | – |
| Minimum value of CKMB post-PCI or CAG, U/l | 19 | 20 | – |
| Maximum value of troponin I pre-PCI, ng/ml | 0.9 | 0.81 | – |
| Minimum value of troponin I post-PCI or CAG, ng/ml | 0.9 | 0.21 | – |
| Procedural details | |||
| Drug-eluting stent (%) | 66 (100) | – | |
| Stent surface per subject, 2πR × length, mm2 | 335.59±234.99 | – |
Unless otherwise indicated, data are expressed as mean ± standard deviation or rate. Significant differences between the two groups are found for diabetes history, family history of coronary disease and the extent of the coronary artery lesion. BMI, body-mass index; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; Hs-CRP, high sensitivity C-reactive protein; PCI, percutaneous coronary intervention; CAG, coronary angiography; CKMB, creatine kinase; R, radius; NS, not significant.