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. 2015 Jul 16;9:3607–3616. doi: 10.2147/DDDT.S85525

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© 2015 Liang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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PIK3CA expression is associated with miR203 and phosphorylation of AKT.

Notes: (A) Expression of miR203 in 107 pairs of gastric carcinoma and adjacent nontumorous tissues. Expression levels of miR203 were normalized to the corresponding levels of U6. (B) PIK3CA expression level was negatively correlated with miR203 expression level. (C, D) Survival relevance analysis of miR203 expression in gastric carcinoma. (E) Serial sections of human gastric carcinoma tissue were subjected to immunohistochemistry (IHC) staining with antibodies against PIK3CA and pAKT. (F) The box plots show the correlation between PIK3CA and pAKT in 107 gastric cancer patients by IHC assays. (G) Western blot analyzed the relationship between PIK3CA and pAKT and showed that PIK3CA positively correlated with pAKT. (H, I) Comparison of overall survival (OS) and disease-free survival (DFS) by pAKT. P<0.05.