Table 3.
Demographic characteristics and clinical manifestations in patients with necrotizing fasciitis, with severe sepsis and without severe sepsis (n=1,452)*
| Characteristics | Severe sepsis (n = 237) | Without severe sepsis (n = 1,215) | P-value |
|---|---|---|---|
| Sex | 0.027 | ||
| Male | 118 (49.8) | 700 (57.7) | |
| Female | 119 (50.2) | 514 (42.3) | |
| Age (years) | <0.001 | ||
| <60 | 77 (32.9) | 594 (49.3) | |
| ≥60 | 157 (67.1) | 611 (50.7) | |
| BMI | 0.668 | ||
| ≤18.50 | 27 (13.1) | 162 (14.9) | |
| 18.51–29.99 | 161 (78.2) | 844 (77.6) | |
| ≥30.00 | 18 (8.7) | 81 (7.5) | |
| Education | <0.001 | ||
| No education | 135 (57.2) | 483 (39.8) | |
| Primary education | 97 (41.1) | 648 (53.4) | |
| Secondary education | 4 (1.7) | 56 (4.6) | |
| Bachelor’s degree and more | 0 (0.0) | 26 (2.2) | |
| Occupation | 0.010 | ||
| Elderly who stays at home | 129 (54.4) | 537 (44.2) | |
| Farmers/laborers | 101 (42.6) | 612 (50.4) | |
| Officials | 7 (3.0) | 65 (5.4) | |
| Underlying disease | |||
| Diabetes | 70 (29.5) | 308 (25.4) | 0.195 |
| Heart disease | 29 (12.3) | 61 (5.0) | <0.001 |
| Renal disease | 13 (5.5) | 30 (2.5) | 0.019 |
| Cirrhosis | 14 (5.9) | 42 (3.5) | 0.094 |
| Hypertension | 107 (45.2) | 406 (33.4) | 0.001 |
| Gout | 39 (16.5) | 100 (8.3) | <0.001 |
| Chronic alcoholism | 40 (16.9) | 185 (15.2) | 0.556 |
| Wound appearance | |||
| Soft tissue swell | 193 (81.4) | 1,018 (83.8) | 0.390 |
| Erythema | 154 (65.0) | 587 (48.3) | <0.001 |
| Bleb | 133 (56.1) | 489 (40.3) | <0.001 |
| Necrosis | 73 (30.8) | 317 (26.1) | 0.149 |
| Gangrene | 8 (3.4) | 29 (2.4) | 0.368 |
| Severe pain | 222 (93.7) | 1,045 (86.1) | 0.001 |
| Site of wound | 0.384 | ||
| Head and neck | 1 (0.4) | 5 (0.4) | |
| Trunk | 7 (3.0) | 19 (1.6) | |
| Upper limb | 47 (19.8) | 213 (17.5) | |
| Lower limb | 175 (73.9) | 952 (78.3) | |
| Fournier’s gangrene | 6 (2.5) | 23 (1.9) | |
| Multiple sites | 1 (0.4) | 3 (0.3) | |
| Hospital | 0.718 | ||
| Chiang Rai | 121 (51.1) | 654 (53.8) | |
| Kamphaeng Phet | 95 (40.1) | 455 (37.5) | |
| Phayao | 21 (8.8) | 106 (8.7) | |
Notes: values are n (%).
*
Some variables have missing data, therefore, the total number of patients in each group maybe different from the number that shown in the title.
Abbreviation: BMI, body mass index.