Figure 6.

Rigid cluster decomposition with individual coloring. Clusters containing four or more atoms are shown in thick lines, the biggest cluster is dark blue. Hydrogen bond constraints are marked as red lines. Left: Protein Data Bank code 3msw. The dominant β-meander motif forms a single rigid cluster, while loops on the lower left remain flexible, consisting of multiple smaller rigid clusters. Right: Protein Data Bank code 1hhp. The central β-meander motif rigidly connects to the α-helix in the background. The rainbow appearance of other motifs like the loops and the three β-hairpins indicates flexibility.