Fig. 1.

The effects of TBQ on the Ca transient. (A) Specimen [Ca²⁺]_i transients measured with Fluo-3. The cell was stimulated at 0.5 Hz with a 100 ms duration depolarising pulse from −40 to 0 mV. TBQ was applied in the concentrations shown. (B) Expanded time base overlays showing averaged transients from (A). Left shows original records and right normalised. (C) Average data (n = 16 cells from 8 animals) showing (left) the amplitude of systolic Ca and (right) rate constant of decay of systolic Ca. All data have been normalised to the values before addition of TBQ (“C”). “W” denotes values after removing the final concentration of TBQ (*p < 0.05 vs. control).