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Anti-proliferative efficacy of TNFα-encoding DNA complexed with DAB-LF, DAB-LFC and DAB in A431, B16-F10 and T98G cells, expressed as IC50 values (n = 15).
| IC50 (μg/mL) (mean ± SEM) |
|||
|---|---|---|---|
| Formulation | A431 | B16F10 | T98G |
| cplx DAB-LF | 2.68 ± 0.63 | 1.88 ± 0.15 | 6.20 ± 0.71 |
| cplx DAB-LFC | 3.66 ± 0.22 | 1.44 ± 0.25 | 5.01 ± 0.48 |
| cplx DAB | 9.47 ± 1.15 | 4.72 ± 0.32 | 29.84 ± 2.79 |
| DAB-LF only | > 100 | > 100 | > 100 |
| DAB-LFC only | > 100 | > 100 | > 100 |
| DAB only | > 100 | > 100 | > 100 |
| DNA only | > 100 | > 100 | > 100 |
