TABLE 2.
Subject demographics in the six pooled eyelash hypotrichosis studies
| CHARACTERISTIC | OVERALL | IDIOPATHIC | POSTCHEMOTHERAPY | |||
|---|---|---|---|---|---|---|
| BIM 0.03% (n=680) | VEH (n=379) | BIM 0.03% (n=534) | VEH (n=328) | BIM 0.03% (n=146) | VEH (n=51) | |
| Age, years Mean (SD) Median Min, max |
48.2 (11.09) 49.0 20, 77 |
47.8 (12.5) 48.0 19, 78 |
47.7 (11.49) 48.0 20, 77 |
47.0 (12.17) 47.0 19, 78 |
50.1 (9.22) 50.5 26, 76 |
52.9 (9.89) 51.0 26, 74 |
| Age distribution, n (%) <45 years 45-65 years ≥65 years |
241 (35.4) 401 (59.0) 38 (5.6) |
141 (37.2) 214 (56.5) 24 (6.3) |
203 (38.0) 299 (56.0) 32 (6.0) |
133 (40.5) 177 (54.0) 18 (5.5) |
38 (26.0) 102 (69.9) 6(4.1) |
8 (15.7) 37 (72.5) 6 (11.8) |
| Sex, n (%) Male Female |
16 (2.4) 664 (97.6) |
16 (4.2) 363 (95.8) |
15 (2.8) 519 (97.2) |
16 (4.9) 312 (95.1) |
1 (0.7) 145 (99.3) |
0 (0.0) 51 (100.0) |
| Race, n (%) Caucasian African American Asian Hispanic Other* |
444 (65.3) 75 (11.0) 135 (19.9) 21 (3.1) 5 (0.7) |
190 (50.1) 53 (14.0) 123 (32.5) 10 (2.6) 3 (0.8) |
341 (63.9) 62 (11.6) 113 (21.2) 13 (2.4) 5 (0.9) |
165 (50.3) 49 (14.9) 103 (31.4) 8 (2.4) 3 (0.9) |
103 (70.5) 13 (8.9) 22 (15.1) 8 (5.5) 0 (0.0) |
25 (49.0) 4 (7.8) 20 (39.2) 2 (3.9) 0 (0.0) |
| Iris color, n (%) Dark* Light‡ Unavailable |
230 (33.8) 311 (45.7) 139 (20.4) |
142 (37.5) 134 (35.4) 103 (27.2) |
173 (32.4) 240 (44.9) 121 (22.7) |
126 (38.4) 117 (35.7) 85 (25.9) |
57 (39.0) 71 (48.6) 18 (25.9) |
16 (31.4) 17 (33.3) 18 (35.3) |
| GEA score, n (%) 1 - Minimal 2 - Moderate |
236 (34.7) 444 (65.3) |
110 (29.0) 269 (71.0) |
132 (24.7) 402 (75.3) |
73 (22.3) 255 (77.7) |
104 (71.2) 42 (28.8) |
37 (72.5) 14 (27.5) |
*
Other race included American Indian, African American, and Caucasian, First Nation (Haida), half African American, and half Guamian, Indonesian, Middle Eastern American, Native Hawaiian Pacific Islander, and Pacific Islander.
†
Dark iris colors included brown and dark brown. If other category contained black, it was grouped as dark.
‡
Light iris colors included blue, blue-gray, blue/gray-brown, gray, green, green-brown, hazel, and other.
Iris color was not collected as part of the study procedures in Studies 2, 3, and 5.
BIM=bimatoprost; GEA=Global Eyelash Assessment; SD=standard deviation; VEH=vehicle