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. Author manuscript; available in PMC: 2015 Jul 21.
Published in final edited form as: J Cell Physiol. 2013 Feb;228(2):292–297. doi: 10.1002/jcp.24148

Fig. 1. Hepatoma cell growth inhibition.

Fig. 1

A. Hep3B, PLC/PRF/5, HepG2 human hepatoma cell lines were cultured in presence of Regorafenib at various concentrations or in solvent alone. At 72 h, cells were harvested for MTT assay. The relative cell viability (%) was calculated as a percentage relative to the untreated control cells.: OD of treated cells / OD of control cells × 100 %.

B. Hep3B cells were cultured in presence of 7.5 μM Regorafenib for either 0-24, 0-48 or 0-72 h and the medium was then changed to drug-free medium or for 0-96 h. All cells were harvested at 96 h and the viability was evaluated by the MTT assay.