Fig. 2. The proportion of the patients who achieved well-controlled asthma in week 12. The proportion test (one-sided) for proving non-inferiority of MON-400BUD vs 800BUD in per-protocol population without the last observation carried forward (LOCF) approach and intention-to-treat set with LOCF, with a predetermined non-inferiority margin of -17.2% for the difference in the rates of well-controlled asthma between treatments. MON-400BUD, montelukast added to low-dose inhaled budesonide; 800BUD, medium-dose inhaled budesonide; PP, per-protocol; ITT, intention-to-treat; LOCF, last observation carried forward; CI, confidence interval.