Skip to main content
. 2015 Jul 21;10(7):e0133243. doi: 10.1371/journal.pone.0133243

Table 4. Relative mean bias percentage, RMSE and coverage probability when N = 30000, m = 30, β 1 = 0.1, β 2 = 0.2, ρ b = 0.6, ρ w = 0.3.

Summary Effects Heterogeneity Correlation
data % Bias RMSE b Coverage % Bias RMSE b % Bias %(ρ^b)
Method scenario I 2, a β^1 β^2 β^1 β^2 β^1 β^2 τ^12 τ^22 τ^12 τ^22 (ρ^b) -1 +1 |1|
MV COM 50% 0 0 0 0 95.1 95.2 0 3 0 0 1 0.7 9.4 10.1
UV COM 0 0 0 0 95.1 95.3 0 3 0 0
MV COM c 0 0 0 0 95.3 95.4 6 6 0 0 40 0.1 39.5 39.6
MV MAR 0 0 0 -2 95.1 94.8 0 3 0 0 -2 1.9 16.3 18.2
UV MAR 0 0 0 0 95.1 95.3 0 3 0 0
MV MIF 0 27 0 -12 95.2 57.8 0 -31 0 -4 -9 6.4 26.8 33.2
UV MIF 0 32 0 0 95.1 49.7 0 -33 0 0
MV COM 75% 0 0 0 0 94.8 94.5 1 0 0 0 -2 0 0.1 0.1
UV COM 0 0 0 0 94.9 94.4 1 0 0 0
MV COM c 0 0 0 0 94.9 94.4 1 1 0 0 15 0 1.7 1.7
MV MAR 0 0 0 -3 94.8 94.1 1 1 0 2 -2 0 0.7 0.7
UV MAR 0 0 0 0 94.9 94.5 1 1 0 0
MV MIF 0 26 0 -16 94.8 76.1 1 6 0 -4 -1 0.1 1 1.1
UV MIF 0 36 0 0 94.9 69.9 1 6 0 0

Abbreviation: RMSE, root mean square error; CI, confidence interval; MV, multivariate meta-analysis; UV, Univariate meta-analysis; COM, complete data scenario; MAR, end point 2 missing at random for 30% studies; MAR, end point 2 missing informatively for 30% studies.

aThe between-study variances for both end-points τj2, j = 1,2 are: τj2 = 0.0036 for I 2 = 50%, τj2 = 0.0109 for I 2 = 75%.

bRMSE of estimates by MV method are expressed as % smaller (-) or larger (+) of corresponding estimates by UV method.

cρ^w  ignored.