Table 4.
Median baseline biomarker immunohistochemistry expression (a) and changes in median biomarker expression from biopsy to surgery (b).
| (a) | ||
|---|---|---|
| Controls (n = 13) |
Anastrozole-treated (n = 13) |
|
| Ki-67, % (range) | 15 (5–45) | 20 (5–60) |
| CD34, No. of cells/hpf (range) | 46 (22–115) | 52 (27–88) |
| TUNEL, % (range) | 1 (0–2) | 1 (0–2) |
| (b) | |||
|---|---|---|---|
| Controls (n = 13) |
Anastrozole-treated (n = 13) |
ΔMedian expression cases versus controls p-value |
|
| Ki-67, % | + 5% (p = .04) | 0% (NS) | 0.03 |
| CD34, No. of cells / hpf | + 14% (p = .01) | + 24% (p = .02) | 0.92 |
| TUNEL, % | 0% (NS) | 0% (NS) | 0.62 |
TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling; NS, not significant