Table 4.
Multivariable Association of Patient Characteristics and Angiographic and CMR Findings With LV End-Diastolic Volume at 6 Months Post-STEMI (n = 267)∗
| Coefficient (95% CI) | p Value | |
|---|---|---|
| Remote zone native T1, ms | 0.16 (0.05 to 0.27) | 0.005 |
| LV end-diastolic volume at baseline, ml | 0.69 (0.59 to 0.79) | <0.001 |
| Infarct size, % LV mass | 0.83 (0.56 to 1.11) | <0.001 |
| Male | 17.82 (10.78 to 24.86) | <0.001 |
| BMI, kg/m2 | 0.67 (0.02 to 1.33) | 0.045 |
| Hypercholesterolemia | −6.85 (−13.65 to −0.05) | 0.048 |
| Sustained ventricular arrhythmia | 12.36 (1.33 to 23.39) | 0.028 |
| Reperfusion mode: successful thrombolysis | 48.91 (5.71 to 92.10) | 0.027 |
The coefficient and 95% CI indicate the magnitude and direction of the difference in LV end-diastolic volume (ml) at follow-up for the patient characteristic (binary or continuous). For example, on average, LV end-diastolic volume (ml) at follow-up was 0.16 (95% CI: 0.05 to 0.27) higher for each 1-ms increase in remote zone native T1 measured by CMR at baseline. The univariable associations with LV end-diastolic volume at 6 months are described in the Online Appendix.
When area at risk was included instead of infarct size, remote zone T1 was also associated with LV end-diastolic volume at follow-up (0.25; 95% CI: 0.09 to 0.41; p = 0.002).