Table 4.
CON (n = 25) | Group A (n = 27) | Group B (n = 26) | Group C (n = 26) | |
---|---|---|---|---|
(95 % CI) | (95 % CI) | (95 % CI) | (95 % CI) | |
LVEDV by echocardiography, ml | ||||
Baseline | 157.7 ± 26.1 | 153.1 ± 27.9 | 151.7 ± 21.8 | 154.5 ± 26.7 |
(148.0 to 167.3) | (141.8 to 165.4) | (142.9 to 160.5) | (143.7 to 165.3) | |
6 months | 156.9 ± 27.2 | 151.2 ± 26.3 | 149.8 ± 23. 5 | 152.8 ± 24.7 |
(144.8 to 168.9) | (139.3 to 162.0) | (138.6 to 158.1) | (142.1 to 163.5) | |
Change from baseline | −2.5 ± 14.5 | −4.0 ± 11.3 | −3.7 ± 12.5 | −3.8 ± 15.4 |
(−8.9 to 3.9) | (−10.5 to 1.8) | (−9.3 to 2.7) | (−10.4 to 2.9) | |
12 months | 157.5 ± 27.6 | 149.4 ± 25.8† | 148.5 ± 20.7† | 150.2 ± 26.0 |
(145.3 to 169.7) | (137.2 to 160.5) | (137.9 to 156.2) | (138.4 to 162.1) | |
Change from baseline | −3.9 ± 18.7 | −7.9 ± 13.9 | −6.6 ± 10.6 | −7.6 ± 18.0 |
(−12.2 to 4.4) | (−14.3 to −0.8) | (−11.5 to −1.4) | (−15.8 to 0.6) | |
LVESV by echocardiography, ml | ||||
Baseline | 93.9 ± 17.3 | 90.8 ± 19.3 | 90.5 ± 18.3 | 97.0 ± 25.1 |
(88.9 to 100.9) | (83.0 to 98.6) | (83.2 to 97.9) | (86.8 to 107.1) | |
6 months | 90.6 ± 21.4 | 77.2 ± 19.0*†‡ | 83.2 ± 14.7 | 92.2 ± 21.6 |
(80.8 to 100.3) | (69.3 to 85.0) | (76.3 to 90.0) | (82.9 to 101.6) | |
Change from baseline | −4.0 ± 10.8 | −13.4 ± 10.0†‡ | −10.5 ± 11.9 | −5.3 ± 12.0 |
(−8.9 to 0.8) | (−17.6 to −9.3) | (−16.0 to −4.9) | (−10.5 to −0.2) | |
12 months | 89.8 ± 22.3* | 71.1 ± 19.8*†‡ | 73.4 ± 17.1*†‡ | 89.1 ± 22.6* |
(80.8 to 100.3) | (62.6 to 79.7) | (64.5 to 82.2) | (78.8 to 99.4) | |
Change from baseline | −6.4 ± 15.9 | −20.5 ± 13.3†‡ | −19.6 ± 11.1†‡ | −9.4 ± 16.3 |
(−13.3 to 0.4) | (−26.2 to −14.7) | (−25.3 to −13.9) | (−16.8 to −1.9) |
* p < 0.05, vs baseline; † p < 0.05, vs control; ‡ p < 0.05, vs group C. CON control group; group A bone marrow mononuclear cell (BMC) infusion within 1 day after percutaneous coronary intervention (PCI); group B BMC infusion at 3–7 days after PCI; group C BMC infusion at 7–30 days after PCI; LVEDV left ventricular end-diastolic volume; LVESV left ventricular end-systolic volume