Table 1.
Demographic characteristics, clinical symptoms, and histological features of study population
| Study population (n = 88,517) | Esophageal eosinophiliaa (n = 4,101) | |
|---|---|---|
| Demographic characteristic | ||
| Age (yrs) mean ± SD | 51.1 ± 18.2 | 39.6 ± 17.6 |
| Male n (%) | 33,786 (38.2) | 2,347 (57.2) |
| Clinical symptoms/EGD indicationsb – n (%) | ||
| Dysphagia/odynophagia | 14,558 (16.5) | 1,510 (36.8) |
| Heartburn | 38,470 (43.4) | 1,562 (38.1) |
| Chest pain | 3,091 (3.5) | 126 (3.1) |
| Abdominal pain/dyspepsia | 46,132 (52.1) | 1,843 (44.9) |
| Nausea/vomiting | 10,826 (12.2) | 474 (11.6) |
| Weight loss | 5,059 (5.7) | 145 (3.5) |
| Diarrhea | 11,864 (13.4) | 533 (13.0) |
| Histological features | ||
| Maximum eosinophil count, mean ± SD | 2.9 ± 11.9c | 36.6 ± 23.9 |
| Eosinophil microabscesses n (%) | 929 (1.1) | 929 (22.7) |
a
Patients with esophageal eosinophilia on esophageal biopsy with a minimum count of ≥ 15 eos/hpf and with an EoE pathology code
b
Multiple indications could be listed for each procedure
c
Includes 52,393 patients with normal or documented number of esophageal eosinophils on biopsy