Table 1.

IPA canonical pathways regulated by IFN-γ

Canonical pathways	Up-regulated	Down-regulated	Not detected	Total
EIF2 Signaling	9.9%	79.1%	11%	172
Antigen presentation pathway	70.3%	13.5%	16.2%	37
tRNA charging	2.6%	92.1%	5.3%	38
Purine nucleotides synthesis	0%	90.9%	9.1%	11
Regulation of eIF4 and p70S6K	12.7%	71.1%	16.2%	142
Crosstalk between DCs and NKs	41.6%	12.4%	46.1%	89
mTOR Signaling	13.7%	63.2%	23.1%	182

Ingenuity Pathway Analysis (IPA) of canonical pathways most enriched at the level of ribosome footprint frequency (RPF); ranked by P-value (indicated in Fig. 7a). The percentages of genes detected in each category (up- or down-regulated by IFN-γ, or not detected) are listed. Data was generated from merged dataset of two biological replicates.