Table 2.
miRNA | Expression (log2 fold) | p-value | FDR |
---|---|---|---|
hsa-miR-146b-3p | –2.56 | 8.35E–07 | 0.0005 |
hsa-miR-4662a-5p | –2.70 | 1.71E–06 | 0.0005 |
hsa-miR-99b-5p | –2.27 | 3.89E–06 | 0.0008 |
hsa-miR-146b-5p | –2.46 | 3.76E–05 | 0.0050 |
hsa-miR-654-3p | –2.66 | 8.75E-04 | 0.0559 |
hsa-miR-125a-5p | –1.56 | 8.96E-04 | 0.0559 |
hsa-let-7e-3p | –1.98 | 1.30E-03 | 0.0653 |
miRNAs most significantly suppressed by IFN-γ in TLR-stimulated macrophages (p < 1.3E−03, FDR<0.0653). Expression (log2 fold) was calculated as relative miRNA expression by comparing IFN-γ-treated and control condition; Expression (log2 fold)=log2(IFN-γ/control) Statistical analysis was performed using edgeR.