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. Author manuscript; available in PMC: 2016 Jul 21.
Published in final edited form as: Anal Chem. 2015 Jul 2;87(14):7022–7029. doi: 10.1021/acs.analchem.5b01724

Figure 3.

Figure 3

Changes to HX when melittin interacts with monolayers. (A) Cartoon representation of melittin interacting with a DPPS monolayer in a parallel position (top, adapted from Ref.39) or in a perpendicular position (bottom, Ref. 45,46). (B) Relative deuterium incorporation at the times indicated for melittin when monolayer associated and labeled within the trough (red) versus when labeled in solution with a conventional HX protocol (blue). The average of three independent measurements is shown with error bars indicating the spread of the measurements.