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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Neural Eng. 2015 May 27;12(4):046002. doi: 10.1088/1741-2560/12/4/046002

Figure 3.

Figure 3

Neuronal nuclei densities and viability around implanted microelectrodes. Neuronal nuclei (NeuN) and fluorojade-C labeling was assessed at two (A-G) and sixteen (H-N) weeks following device implantation in tested animal groups. At two weeks, no statistical differences between animal conditions were noted (G). However, all conditions, from 0 to 50 µm, demonstrated significantly lower densities than background (*p<0.05). By sixteen weeks, only changes were noted in fluorojade-C labeling, where daily diluent and daily resveratrol animals had smaller populations of degenerating neurons (I, K, M). Only the binning region of 0 to 50 µm had significantly lower densities than background (N; *p<0.05). Data represent average ± s.e.m. N≥4. Scale = 100 µm.