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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Mucosal Immunol. 2015 Jan 21;8(5):1047–1059. doi: 10.1038/mi.2014.132

Figure 4.

Figure 4

CXCL13 and TNFα levels are increased following Helicobacter infection in the absence of IRAK-M. (a) Gastric tissue from WT and IRAK-M KO mice infected with H. felis for four weeks were evaluated for cytokines associated with lymphoid neogenesis. Cytokine expression was determined by semi-quantitative PCR using RNA purified from gastric tissue (n = 8; ± SD). (b) WT and IRAK-M KO mice infected with H. felis were evaluated for CXCL13 and TNFα over 28 days. Expression was determined by semi-quantitative PCR used purified RNA from gastric tissue (n = 3 per time point per mouse strain; ± SEM). * P<0.05. (c) Paraffin embedded tissues were stained for CXCL13 by immunohistochemistry (Left) or by in situ hybdridization with CXCL13 RNA-specific probes (right).