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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Mucosal Immunol. 2015 Jan 21;8(5):1047–1059. doi: 10.1038/mi.2014.132

Figure 6.

Figure 6

Helicobacter induces ILC dependent increases in calprotectin. (a) Groups of rag1−/− mice were infected with H. felis and treated with ILC-depleting antibody (anti-CD90.2) or an isotype matched control antibody. Bacterial load was determined by PCR quantification of 16S RNA gene copy number per gram of stomach tissue (± SD). Host expression of (b) RegIIIγ and (c) calprotectin proteins S100A8 and S100A9 were determined by semi-quantitative PCR using RNA isolated from gastric tissue (± SEM). (d)Groups of rag1−/− mice were infected with H. pylori SS1 for 28 days and calprotectin protein levels were determined by semi-quantitative PCR (± SEM). (e) Cytokine expression was determined by semi-quantitative PCR using RNA isolated from the gastric tissue the groups described in (a) (± SEM).