Table 2.
Comparison of clinical healing score and histological healing score compared between the Botroclot and control groups
| Poor | Moderate | Good | Excellent | Test of significance* | ||
|---|---|---|---|---|---|---|
| z-score | p value | |||||
| Clinical scoring on day 7, day 14 and day 21 | ||||||
| Day 7 | ||||||
| Control (n = 38) | 1 (2.6 %) | 16 (42.1 %) | 21 (55.3 %) | – | −0.209 | 0.835 |
| Botroclot (n = 38) | 1 (2.6 %) | 17 (44.7 %) | 20 (52.6 %) | – | ||
| Day 14 | ||||||
| Control (n = 38) | 1 (2. %) | 13 (34.2 %) | 23 (60.5 %) | 1 (2.6 %) | −1.706 | 0.088 |
| Botroclot (n = 38) | – | 8 (21.1 %) | 28 (73.7 %) | 2 (5.3 %) | ||
| Day 21 | ||||||
| Control (n = 38) | 1(2.6 %) | 5 (13.2 %) | 31 (81.6 %) | 1 (2.6 %) | −1.459 | 0.145 |
| Botroclot (n = 38) | – | 3 (7.9 %) | 32 (84.2 %) | 3 (7.9 %) | ||
| Histological scoring on day 7, day 14 and a combined analysis | ||||||
| Day 7 | ||||||
| Control (n = 16) | 7 (43.8 %) | 8 (50 %) | 1 (6.3 %) | 1.565 | 0.118 | |
| Botroclot (n = 18) | 8 (44.4 %) | 3 (16.7 %) | 6 (33.3 %) | 1 (5.6 %) | ||
| Day 14 | ||||||
| Control (n = 20) | – | 10 (50 %) | 8 (40 %) | 2 (10 %) | 2.511 | 0.012 |
| Botroclot (n = 19) | – | 2 (10.5 %) | 6 (31.6 %) | 11 (57.9 %) | ||
| Combined overall analysis | ||||||
| Control (n = 36) | 7 (19.4 %) | 18 (50 %) | 9 (25 %) | 2 (5.5 %) | 2.898 | 0.004* |
| Botroclot (n = 37) | 8 (21.6 %) | 5 (13.5 %) | 12 (32.4 %) | 12 (32.4 %) | ||
* Wilcoxon signed rank test (p ≤ 0.05 = significant)