Table 1.
The effect of DMSO (0.5%), imperatorin (75 μM), and verapamil (10 μM) on the spontaneous motoric activity of rat isolated jejunum specimens.
| Basal tone | AUC | |
|---|---|---|
| DMSO (0.5%) | −0.45 ± 4.92∗# | 0.21 ± 4.16∗# |
| Imperatorin (75 μM) | 188.04 ± 50.54∗▲# | 181.43 ± 31.65∗▲ |
| Imperatorin (100 μM) | 208.41 ± 29.37∗▲# | 237.03 ± 45.41∗▲ |
| Verapamil (10 μM) | 179.62 ± 24.37∗▲ | 211.10 ± 41.17∗▲ |
The results are expressed as % of the relaxation caused by isoproterenol applied in the reference dose 0.1 μM. The relaxation provoked by isoproterenol in the reference dose is expressed as 100%. The results are expressed as mean from 6-7 independent experiments (±SD). ∗ p ≤ 0.05 versus Isop, ▲ p ≤ 0.05 versus DMSO, 0.5%, and # p ≤ 0.05 versus verapamil.