Table 2. Cumulative lifetime pesticide use and mean relative telomere length.
Ever Use | Lifetime Days 1 | Lifetime Intensity Weighted Days 2 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Cumulative Pesticide Use 3 | N | Mean RTL 4 | SE 4 | P 4 , 5 | N | Mean RTL 4 | SE 4 | P 4 , 5 | N | Mean RTL 4 | SE 4 | P 4 , 5 |
HERBICIDE | ||||||||||||
Alachlor a | ||||||||||||
Not Used | 187 | 1.04 | 0.04 | 187 | 1.04 | 0.04 | 187 | 1.04 | 0.04 | |||
Used | 381 | 1.11 | 0.03 | 0.17 | - | - | - | - | - | - | ||
Low | - | - | - | 135 | 1.05 | 0.05 | 121 | 1.06 | 0.05 | |||
Medium | - | - | - | 109 | 1.17 | 0.05 | 122 | 1.15 | 0.05 | |||
High | - | - | - | 124 | 1.17 | 0.05 | 0.03 | 122 | 1.18 | 0.05 | 0.04 | |
Butylate a | ||||||||||||
Not Used | 344 | 1.10 | 0.03 | 344 | 1.10 | 0.03 | 344 | 1.10 | 0.03 | |||
Used | 224 | 1.02 | 0.04 | 0.04 | - | - | - | - | - | - | ||
Low | - | - | - | - | 55 | 0.96 | 0.07 | 54 | 0.98 | 0.07 | ||
Medium | - | - | - | - | 48 | 1.05 | 0.07 | 56 | 1.01 | 0.07 | ||
High | - | - | - | - | 63 | 0.98 | 0.06 | 0.01 | 55 | 1.00 | 0.07 | 0.01 |
2,4-D b | ||||||||||||
Not Used | 99 | 1.22 | 0.06 | 99 | 1.22 | 0.06 | 99 | 1.22 | 0.06 | |||
Used | 469 | 1.03 | 0.03 | 0.01 | - | - | - | - | - | - | ||
Low | - | - | - | - | 155 | 1.17 | 0.05 | 151 | 1.11 | 0.05 | ||
Medium | - | - | - | - | 145 | 1.04 | 0.05 | 152 | 1.10 | 0.05 | ||
High | - | - | - | - | 168 | 1.01 | 0.04 | 0.001 | 152 | 0.96 | 0.05 | 0.0003 |
INSECTICIDE | ||||||||||||
Diazinon c | ||||||||||||
Not Used | 284 | 1.15 | 0.04 | 284 | 1.15 | 0.04 | 284 | 1.15 | 0.04 | |||
Used | 284 | 1.06 | 0.03 | 0.15 | - | - | - | - | - | - | ||
Low | - | - | - | - | 73 | 1.11 | 0.07 | 62 | 1.13 | 0.07 | ||
Medium | - | - | - | - | 55 | 0.99 | 0.07 | 63 | 1.03 | 0.07 | ||
High | - | - | - | - | 64 | 0.98 | 0.07 | 0.002 | 63 | 0.99 | 0.07 | 0.004 |
1 Days per year x number of years
2 Lifetime days x intensity score
3 Cumulative use from enrollment and two follow-up questionnaires
4 Adjusted for age at blood draw and: ametolachlor, balachlor, cmetalaxyl
5 Linear regression using log(RTL) and categorical pesticide use (never, low, medium, high)