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Structures of subtilin-like lantibiotics subtilin, entianin, and ericin S, produced by diverse B. subtilis strains, and nisin A, produced by diverse Lactococcus lactis strains. Amino acid residues of ericin S, entianin, and nisin A that differ from those in subtilin are highlighted in gray. Amino acid position 20 is indicated by aa 20. A-S-A, meso-lanthionine; Abu-S-A, 3-methyllanthionine (Abu refers to α-aminobutyric acid); Dha, 2,3-didehydroalanine; Dhb, 2,3-didehydrobutyrine.
