Table 2. Within and between-group activations of extended brain regions during the performance of the task.
| Healthy controls | AN patients | Group comparisons | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Anatomy 1 | Stats 2 | Anatomy 1 | Stats 2 | Anatomy 1 | Stats 2 | |||||||||||||
| x | y | z | KE | Z | x | y | z | KE | Z | x | y | z | KE | Z | ||||
| Acceptance > neutral contrast | Healthy controls> AN patients | |||||||||||||||||
| Medial superior frontal cortex (BA 8 and BA9, extending to BA6 and BA10) | -14 | 48 | 38 | 5 133 | 4.95 | Medial superior frontal cortex (BA 8 and BA9, extending to BA10) | -10 | 36 | 60 | 1 104 | 3.92 | Medial superior frontal cortex (BA8, extended to BA9) | 10 | 32 | 50 | 127 | 3.38 | |
| 10 | 28 | 62 | 4.56 | 6 | 48 | 34 | 3.34 | 10 | 28 | 62 | 2.87 | |||||||
| -14 | 36 | 56 | 4.39 | -8 | 54 | 34 | 3.30 | |||||||||||
| Left dorsolateral prefrontal cortex/left anterior insular cortex | -48 | 14 | 24 | 2 000 | 4.08 | Left parahippocampus, extended to hippocampus, fusiform and amygdala cortices | -34 | -12 | -22 | 330 | 3.75 | |||||||
| -40 | 2 | 40 | 3.82 | -30 | -14 | -14 | 3.46 | |||||||||||
| -44 | 2 | 50 | 3.71 | -38 | -20 | -26 | 3.45 | |||||||||||
| Left temporo-parietal junction | -56 | -56 | 46 | 696 | 4.01 | |||||||||||||
| -50 | -60 | 52 | 3.42 | Healthy controls<AN patients | ||||||||||||||
| -52 | -58 | 30 | 3.37 | No areas | ||||||||||||||
| Right frontal operculum/right anterior insular cortex | 46 | 32 | -8 | 462 | 3.95 | |||||||||||||
| 52 | 26 | -2 | 3.85 | |||||||||||||||
| 46 | 26 | -14 | 3.68 | |||||||||||||||
| Bilateral ventral striatum (caudate) | 8 | 10 | 10 | 125 | 3.45 | |||||||||||||
| -6 | 8 | 8 | 3.21 | |||||||||||||||
| Rejection > neutral contrast | Medial superior frontal cortex | -8 | 44 | 52 | 3 580 | 5.34 | Medial superior frontal cortex | -4 | 52 | 22 | 2 302 | 4.77 | Healthy controls> AN patients | |||||
| -8 | 50 | 44 | 5.07 | -8 | 38 | 58 | 4.54 | No areas | ||||||||||
| 12 | 42 | 50 | 4.59 | -12 | 54 | 32 | 3.94 | |||||||||||
| Left inferior frontal cortex, triangular and orbital parts/Left anterior insular cortex. | -50 | 18 | 6 | 680 | 4.12 | Right inferior frontal gyrus, operculum/right anterior insular cortex | 32 | 24 | -18 | 250 | 3.91 | |||||||
| -38 | 26 | -16 | 3.45 | Left inferior frontal gyrus, operculum/ Left anterior insular cortex. | -30 | 16 | -24 | 276 | 3.26 | |||||||||
| -44 | 36 | -16 | 3.32 | -28 | 22 | -10 | 3.01 | |||||||||||
| Right inferior frontal cortex, triangular and opercular parts/right anterior insular cortex | 52 | 28 | -6 | 292 | 4.00 | -48 | 30 | -14 | 3.00 | |||||||||
| 60 | 24 | 20 | 2.82 | Left ventral striatum (caudate) | -8 | 6 | 4 | 155 | 2.97 | Healthy controls<AN patients | ||||||||
| 52 | 24 | 10 | 2.81 | -6 | 14 | -6 | 2.90 | Visual cortex (BA18) | -30 | -98 | 6 | 262 | 3,79 | |||||
| Left middle temporal cortex | -50 | -42 | -2 | 226 | 3.38 | Left visual cortex (BA17, BA18) | -32 | -98 | 4 | 1 437 | 5.14 | |||||||
| -52 | -30 | -8 | 2.86 | -38 | -58 | -16 | 3.57 | |||||||||||
| Visual cortex (BA17) | 12 | -92 | 4 | 281 | 3.86 | -36 | -74 | -12 | 3.55 | |||||||||
| Right visual cortex (BA17, BA18), Fusiform gyrus | 28 | -98 | 0 | 1 260 | 4.78 | |||||||||||||
| 22 | -80 | -14 | 3.50 | |||||||||||||||
| 12 | -88 | 12 | 3.27 | |||||||||||||||
1 Activity co-ordinates (x, y, z) are given in Montreal Neurological Institute (MNI) Atlas space.
2 Magnitude and extent statistics correspond to a minimum threshold of P FWE < 0.05 (cluster corrected at whole-brain).
KE = cluster size.
BA = Brodmann area.