Table 1.

Summary of experimental groups, interventions, and sample sizes

Experimental group	Treatment	Animal no.
Sham	None	13
SBI + vehicle	Vehicle, i.p.	32
SBI + AS252424 3 mg/kg	AS252424 3 mg/kg, i.p.	8
SBI + AS252424 10 mg/kg	AS252424 10 mg/kg, i.p.	21
SBI + AS252424 10 mg/kg + human recombinant active-PI3Kγ	AS252424 10 mg/kg, i.p.; human recombinant active-PI3Kγ 200 ng, i.c.v.	13
SBI + AS252424 10 mg/kg + human recombinant active-PDE3B	AS252424 10 mg/kg, i.p.; human recombinant active-PDE3B 100 ng, i.c.v.	6
SBI + AS605240 10 mg/kg	AS605240 10 mg/kg, i.p.	7
SBI + scramble siRNA	Scramble siRNA, i.c.v.	15
SBI + PI3K p110γ siRNA	PI3K p110γ siRNA 500 pmol, i.c.v.	15

i.p., Intraperitoneally; i.c.v., intracerebroventricularly.