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Blunted feeding response to NPY in Pdx1-Cre:Vgatflox/flox mice. All mice were implanted with intracerebroventricular (icv) cannulation, which was verified by angiotensin-induced drinking behavior. Food intake response male Vgatflox/flox and Pdx1-Cre:Vgatflox/flox mice to intracerebroventricular administration of NPY (A), overnight fasting (B), and Muscimol (C). All data presented as mean ± SEM, n = 5–8; *p < 0.05 and **p < 0.01, two-way ANOVA tests followed by a Tukey correction.
